Table 1. Effect of treatment with canagliflozin (C) on some physiological parameters in rats with adenine (A)-induced chronic kidney disease (CKD). Values in the table are means ± SEM (n = 6). CKD was induced by the inclusion of A in the feed at a concentration of 0.25%^w/w for 35 days, and C was given to rats concurrently by oral gavage. On the 35^th day of treatment, the rats were placed in metabolic cages to collect urine. Different superscripts indicate significance as follows (P < 0.05 was considered significant): ^a Control vs all groups. ^b A vs adenine treated groups